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Kaori (カオリ) was Tetsuo Shima's love interest in both the anime and manga versions. Her role differs from the manga, but her personality remains constant as that of a shy and timid girl.

She stood by Tetsuo, even though he treated her with abuse in the hopes of appearing tough to his friends. When Tetsuo began his rampage through Neo-Tokyo, she followed him, and when his powers manifested and caused his body to warp and expand to grotesque proportions, she was engulfed in his flesh and crushed to death by his oversized organs.